15 KDa Selenoprotein (SEP15) (C-Term) Peptide
SEP15
Reactivity: Human, Rat
Host: Synthetic
BP, WB
Catalog No. ABIN1541066
Quick Overview for 15 KDa Selenoprotein (SEP15) (C-Term) Peptide (ABIN1541066)
Target
Sep 15 (SEP15)
(15 KDa Selenoprotein (SEP15))
Origin
Human, Rat
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- LFRGLQIKYV RGSDPVLKLL DDNGNIAEEL SILKWNTDSV EEFLSEKLER
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-sep15 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Sep 15 (SEP15) (15 KDa Selenoprotein (SEP15))
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Background
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This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. The exact function of this protein is not known, however, it has been found to associate with UDP-glucose:glycoprotein glucosyltransferase (UGTR), an endoplasmic reticulum(ER)-resident protein, which is involved in the quality control of protein folding. The association with UGTR retains this selenoprotein in the ER, where it may play a role in protein folding.
Alias Symbols: -
Protein Interaction Partner: Rpl30
Protein Size: 162 -
Molecular Weight
- 17 kDa
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Gene ID
- 113922
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NCBI Accession
- NM_133297, NP_579831
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UniProt
- Q923V8
Target
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